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以脱镁叶绿酸-α甲酯1为原料,在酸性条件下加热,将其转化为焦脱镁叶绿酸-α甲酯2.选择四氧化锇为氧化剂将其3-位乙烯基氧化成甲酰基,在......
具有新颖共轭顺-烯二炔结构的天然产物可精巧地引发顺-烯二炔的闭环反应而产生双自由基,从癌细胞DNA糖磷脂骨架上夺取氢原子,促成......
Oxidation-strengthened disulfide-bridged prodrug nanoplatforms with cascade facilitated drug release
One of the major barriers in utilizing prodrug nanocarriers for cancer therapy is the slow release of parent drug in tum......